“The results show, once again, Dr. Leibel said, that losing weight ‘is not a neutral event,’ and that it is no accident that more than 90 percent of people who lose a lot of weight gain it back (emphasis added). ‘You are putting your body into a circumstance it will resist,’ he said. ‘You are, in a sense, more metabolically normal when you are at a higher body weight.’
“A solution might be to restore hormones to normal levels by giving drugs after dieters lose weight. But it is also possible, said Dr. Jules Hirsch of Rockefeller University, that researchers just do not know enough about obesity to prescribe solution (emphasis added).
“One thing is clear, he said: ‘A vast effort to persuade the public to change its habits just hasn’t prevented or cured obesity.’
“’We need more knowledge,’ Dr. Hirsch said. ‘Condemning the public for their uncontrollable hedonism and the food industry for its inequities just doesn’t seem to be turning the tide (emphasis added).'”
Excerpt from NEW YORK TIMES article on Australian study finding that hormone and metabolic level changes were long-lasting and possibly contributed to weight gain in long-term dieters, even after a “successful” weight loss with maintenance diet